A stoppage-time goal by Lazio defender Adam Marusic downed Juventus 1-0 and gave coach Igor Tudor a winning debut in Serie A.
Marusic headed home a last-gasp cross by substitute Matteo Guendouzi to secure the victory in Rome.
Lazio rose past defending champions Napoli into seventh place, while Juventus were left in third with one win in nine.
Tudor replaced Maurizio Sarri two weeks ago before the international break. As a player, Tudor helped Juventus win Italian titles in 2002 and 2003 while making 112 career appearances in the league for them.
Earlier on Saturday Napoli players took a knee before their 3-0 loss to Atalanta at Diego Maradona Stadium in a public show of support for teammate Juan Jesus.
The gesture came after a sports judge ruled Inter Milan defender Francesco Acerbi will not face sanctions for allegedly racially abusing Jesus, who is Black, in a Serie A match because there wasn’t enough proof.
Aleksei Miranchuk and Gianluca Scamacca took advantage of some timid defending to give Atalanta a two-goal lead before half-time. Teun Koopmeiners completed the win with a late goal for the visitors.
Torino beat ten-man Monza 1-0 and relegation-threatened Frosinone drew at Genoa 1-1.